What is Hyalgan®?

Hyalgan® is a solution that contains a natural substance called hyaluronate. Hyaluronate is normally found in the fluid that lubricates and cushions your knee joint. Hyalgan® is injected into your knee to relieve pain due to osteoarthritis. Hyalgan® is a treatment option for people who do not get Adequate Pain Relief from simple painkillers (like Tylenol® or Advil®) or from exercise and physical therapy. Hyalgan® injections can be used in addition to prescription pain relievers. Hyalgan® is injected directly into your knee by your health care provider. Hyalgan® is a 5-injection regimen given at weekly intervals that provides long-lasting pain relief for up to 6 months. Some patients get benefits with 3 injections given at weekly intervals.

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Important Safety Information About Hyalgan®

Hyalgan® is contraindicated in patients with known hypersensitivity to hyaluronate preparations or in cases of Present Infections or Skin Diseases in the area of the injection site. Use caution when injecting Hyalgan® into patients who are allergic to avian proteins, feathers, and egg products. The safety and effectiveness of Hyalgan® have not been established in children or in pregnant or lactating women, for use in other joints, or for concomitant use with other injectables. It is unknown whether Hyalgan® is excreted in human milk. The effectiveness of a single treatment cycle of fewer than 3 injections has not been established. Transient increases in inflammation in the injected knee following Hyalgan® injection have been reported in some Patients With Inflammatory Arthritis and should not be injected if objective signs of inflammation are present. Transient pain and/or swelling of the injected joint may occur after intra-articular injection of Hyalgan®. Anaphylactoid and allergic reactions have been reported with the use of this product.

Side Effects of Hyalgan®:

Common side effects include but are not limited to:

  • Injection-site Pain
  • Gastrointestinal Complaints
  • Headache
  • Local Ecchymosis (Bruising)
  • Rash
  • Local Joint Pain And Swelling
  • Local Pruritus (Itching)
  • Knee Swelling
  • Effusion
  • Ecchymosis
  • Pruritus
  • Warmth, Pain, Redness, Stiffness, Bruising, Or Puffiness Where The Medicine Was Injected
  • Nausea, Stomach Pain
  • Trouble Walking
  • Swelling In Your Hands Or Feet
  • Back Pain, Joint Pain, Muscle Pain
  • Numbness Or Tingly Feeling
  • Headache, Dizziness
  • Runny Or Stuffy Nose, Sneezing, Sore Throat
  • Fever Or Chills
  • Headache
  • Muscle Pain Or Cramps
  • Severe Pain; Warmth Or Swelling Of One Or More Joints

This is not a complete list of side effects and others may occur.

Cautions To Take Hyalgan®:

You should not receive an Hyalgan® if you have an Infection In Your Knee Or In The Skin around your knee.
You should not receive Hyalgan® if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.
Hyalgan® is not approved for use by anyone younger than 21 years old.
Tell your doctor if you have ever had:

  • Blood Clots Or Circulation Problems In Your Legs
  • An Allergy To Birds, Feathers, Or Egg Products.

It is not known whether Hyalgan® will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.

Frequently Asked Questions

1. How is Hyalgan® given?

Hyalgan® is injected directly into your knee joint. A healthcare provider will give you this injection. To prevent pain and swelling, you will be recommended to rest or apply ice for a short time after your injection.

2. What form does Hyalgan® come in?

Hyalgan® comes in an injection form. Each prefilled syringe contains 2 mL of sterile medication for injection. Each mL of sterile, thick liquid contains 10 mg of hyaluronic acid obtained from rooster combs.

3. What should I consider after taking Hyalgan® treatment?

Do not strain your knee joint for two days after receiving Hyalgan® Injection. Avoid activities such as strenuous sports and exercise, or standing on your feet for a long time.
Inform your doctor if knee pain or swelling continues for a long time or becomes worse after receiving the medication.

4. What are the benefits of Hyalgan®?

Osteoarthritis is a condition that causes pain and stiffness in the joints. Hyalgan® Injection helps relieve pain and reduces inflammation and swelling in your joints due to this condition. This will ensure that you have a better, more active, quality of life.

5. Who should not take Hyalgan®?

Do not use Hyalgan® if you:

  • Are Allergic To Hyaluronic Acid (Sodium Hyaluronate) Or Any Ingredients Of The Medication
  • Are Allergic To Bird Proteins (Also Called Avian Proteins)
  • Have An Infection Or Skin Disease Surrounding The Injection Area